by Lluis Llorens | Nov 19, 2022 | Named Reactions
FollowFollowFollow Van Leusen Reaction The Van Leusen reaction allows the transformation of ketones into nitriles, aldehydes into oxazoles, and aldimines into imidazoles by the reaction of each substrate with tosylmethyl isocyanide (TosMIC). Van Leusen Reaction...
by Lluis Llorens | Nov 17, 2022 | Named Reactions
FollowFollowFollow Transesterification Reaction The Transesterification reaction is the process of exchanging the alkoxy group of an ester with another alcohol. The reaction is catalyzed by the addition of an acid (which protonates the carbonyl group and makes the...
by Lluis Llorens | Nov 17, 2022 | Named Reactions
FollowFollowFollow Stork Enamine Synthesis The Stork enamine synthesis involves the alkylation or acylation of an enamine with the corresponding reagent. General features: 1. The preparation of the enamines takes place with one equivalent of a secondary amine. 2....
by Lluis Llorens | Nov 17, 2022 | Named Reactions
FollowFollowFollow Skraup Reaction The Skraup synthesis is the reaction between anilines and glycerol in the presence of sulfuric acid and an oxidizing agent to deliver the corresponding quinolines. Skraup Reaction Reaction Mechanism 1. The glycerol is dehydrated to...
by Lluis Llorens | Nov 17, 2022 | Named Reactions
FollowFollowFollow Shapiro Olefination The Shapiro olefination allows the preparation of alkenes from the corresponding aldehydes or ketones. The reaction involves an intermediate hydrazone, and it is carried out in the presence of 2 equivalents of an organolithium...
by Lluis Llorens | Nov 15, 2022 | Named Reactions
FollowFollowFollow Seyferth-Gilbert Homologation The Seyferth-Gilbert homologation allows the conversion of carbonyl compounds to the corresponding terminal or internal alkynes with the aid of alpha-diazophosphonates under basic conditions. Seyferth-Gilbert...
