by Lluis Llorens | Mar 9, 2024 | Named Reactions, Nezaradené
The Chemists’ Cookbook Waitlist Are you interested in the Chemists' Cookbook? Join the exclusive waitlist and be the first to know when my new book is released. As a waitlist member, you will get a special pre-launch discount on the book. You're in! Name...
by Lluis Llorens | Apr 15, 2023 | Named Reactions
FollowFollowFollow Mukaiyama Hydration The Mukaiyama hydration allows the transformation of an olefin to the corresponding alcohol with Markovnikov selectivity. General features: 1. The use of a silane reductant allows for this reaction to be carried out without heat....
by Lluis Llorens | Apr 6, 2023 | Named Reactions
FollowFollowFollow Nicholas Reaction The Nicholas reaction allows the conversion of propargylic alcohols to the corresponding substituted alkynes by the reaction with a nucleophile in the presence of dicobalt octacarbonyl and a Lewis acid. Nicholas Reaction Reaction...
by Lluis Llorens | Nov 19, 2022 | Named Reactions
FollowFollowFollow Wacker Oxidation The Wacker-Tsuji oxidation is the one-pot oxidation of olefins to the corresponding ketones with catalytic amounts of Pd(II) salts. Wacker Oxidation Reaction Mechanism 1. Coordination of the alkene. 2. Attack of the coordinated...
by Lluis Llorens | Nov 19, 2022 | Named Reactions
FollowFollowFollow Roush Asymmetric Allylation The Roush asymmetric allylation allows the enantioselective synthesis of homoallylic alcohols from the reaction of allylboronates with aldehydes. General features: 1. The preparation of allylboronates may be achieved by...
by Lluis Llorens | Nov 19, 2022 | Named Reactions
FollowFollowFollow Vilsmeier-Haack Reaction The Vilsmeier-Haack reaction is the formylation reaction of an electron-rich arene using a Vilsmeier reagent. The reagent is prepared from a N,N-disubstituted formamide (such as DMF) and POCl3. General features: 1. The...
