Wacker Oxidation
The Wacker-Tsuji oxidation is the one-pot oxidation of olefins to the corresponding ketones with catalytic amounts of Pd(II) salts.
Wacker Oxidation
Reaction Mechanism
1. Coordination of the alkene. 2. Attack of the coordinated alkene by the nucleophile. 3. β-hydride elimination. 4. 1,2-insertion. 5. β-hydride elimination. 6. Reductive elimination. 7. Catalyst regeneration.
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